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1

Letters to the editor

Giovanni Bonadonna, Paola Corradina, Clara Lechi, Mario Zatti, Domenica de Grandis, Luciano Dalla Libera, Elio Scarpini, Luigi Manfredi, Antonio Marini, Stephen E. Thurston, Lawrence H. Phillips II, W

Journal:

Year:

1984

Language:

english

File:

PDF, 597 KB

english, 1984

2

SPIE Proceedings [SPIE SPIE Optical Engineering + Applications - San Diego, California (Sunday 1 August 2010)] Advanced Wavefront Control: Methods, Devices, and Applications VIII - Adaptive jitter control for tracker line of sight stabilization

Gibson, Steve, Tsao, Tsu-Chin, Herrick, Dan, Beairsto, Christopher, Grimes, Ronnie, Harper, Todd, Radtke, Jeff, Roybal, Benito, Spray, Jay, Squires, Stephen, Tellez, Dave, Thurston, Michael, Dayton, D

Year:

2010

Language:

english

File:

PDF, 2.29 MB

english, 2010

3

Inhibition of Bacteriophage T7 RNA Polymerase in Vitro Transcription by DNA-Binding Pyrrolo[2,1- c ][1,4]benzodiazepines †

Puvvada, Madhu S., Forrow, Stephen A., Hartley, John A., Stephenson, Pauline, Gibson, Ian, Jenkins, Terence C., Thurston, David E.

Journal:

Year:

1997

Language:

english

File:

PDF, 334 KB

english, 1997

4

Oil and Gas Developments in West Coast in 1986

Stephen P. Thurston, Thomas D. Maso,

Journal:

Year:

1987

File:

PDF, 1.03 MB

1987

5

Two distinct deficits of visual tracking caused by unilateral lesions of cerebral cortex in humans

Stephen E. Thurston, Dr. R. John Leigh, Trevor Crawford, Alan Thompson, Christopher Kennard

Journal:

Annals of Neurology

Year:

1988

Language:

english

File:

PDF, 796 KB

english, 1988

6

ChemInform Abstract: Synthesis of a Novel C2/C2′-exo Unsaturated Pyrrolobenzodiazepine Cross-Linking Agent with Remarkable DNA Binding Affinity and Cytotoxicity.

Stephen J. Gregson, Philip W. Howard, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Year:

1999

File:

PDF, 40 KB

1999

7

ChemInform Abstract: Effect of C2/C3-endo Unsaturation on the Cytotoxicity and DNA-Binding Reactivity of Pyrrolo[2,1-c][1,4]benzodiazepines.

Stephen J. Gregson, Philip W. Howard, Simona Barcella, Anthonia Nakamya, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Year:

2000

File:

PDF, 35 KB

2000

8

ChemInform Abstract: Effect of C2-exo Unsaturation on the Cytotoxicity and DNA-Binding Reactivity of Pyrrolo[2,1-c][1,4]benzodiazepines.

Stephen J. Gregson, Philip W. Howard, Kathryn E. Corcoran, Simona Barcella, Maqsood M. Yasin, Abigail A. Hurst, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Year:

2000

File:

PDF, 35 KB

2000

9

ChemInform Abstract: Design and Synthesis of Novel Pyrrolobenzodiazepine (PBD) Prodrugs for ADEPT and GDEPT.

Marina J. Sagnou, Philip W. Howard, Stephen J. Gregson, Ebun Eno-Amooquaye, Philip J. Burke, David E. Thurston

Journal:

Year:

2000

File:

PDF, 35 KB

2000

10

ChemInform Abstract: Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity.

Stephen J. Gregson, Philip W. Howard, John A. Hartley, Natalie A. Brooks, Lesley J. Adams, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Year:

2001

File:

PDF, 34 KB

2001

11

ChemInform Abstract: Synthesis of the First Example of a C2-C3/C2′-C3′-endo Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepine Dimer.

Stephen J. Gregson, Philip W. Howard, Kathryn E. Corcoran, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Year:

2002

File:

PDF, 29 KB

2002

12

Synthesis of the First Examples of A-C8/C-C2 Amide-Linked Pyrrolo[2,1-c][1,4]benzodiazepine Dimers.

Stephen J. Gregson, Philip W. Howard, David E. Thurston

Journal:

Year:

2003

Language:

english

File:

PDF, 169 KB

english, 2003

13

Synthesis and Biological Evaluation of Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 Cyclic Amine Conjugates.

Luke A. Masterson, Stephen J. Croker, Terence C. Jenkins, Philip W. Howard, David E. Thurston

Journal:

Year:

2004

File:

PDF, 128 KB

2004

14

A Novel Approach to the Synthesis of Cytotoxic C2—C3 Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) with Conjugated Acrylyl C2-Substituents.

Zhizhi Chen, Stephen J. Gregson, Philip W. Howard, David E. Thurston

Journal:

Year:

2004

File:

PDF, 193 KB

2004

15

Synthesis of a novel C2/C2′-aryl-substituted pyrrolo[2,1-c][1,4]benzodiazepine dimer prodrug with improved water solubility and reduced DNA reaction rate

Philip W. Howard, Zhizhi Chen, Stephen J. Gregson, Luke A. Masterson, Arnaud C. Tiberghien, Nectaroula Cooper, Min Fang, Marissa J. Coffils, Sarah Klee, John A. Hartley, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 277 KB

english, 2009

16

Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates

Luke A. Masterson, Stephen J. Croker, Terence C. Jenkins, Philip W. Howard, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 173 KB

english, 2004

17

A novel approach to the synthesis of cytotoxic C2–C3 unsaturated pyrrolo[2,1-c]benzodiazepines (PBDs) with conjugated acrylyl C2-substituents

Zhizhi Chen, Stephen J. Gregson, Philip W. Howard, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

18

A new convenient procedure for the synthesis of pyrrolo[2,1-c][l,4]benzodiazepines

Stephen M. Courtney, David E. Thurston

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 135 KB

english, 1993

19

Effect of C2/C3-endo unsaturation on the cytotoxicity and dna-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines

Stephen J. Gregson, Philip W. Howard, Simona Barcella, Anthonia Nakamya, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

20

Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines

Stephen J. Gregson, Philip W. Howard, Kathryn E. Corcoran, Simona Barcella, Maqsood M. Yasin, Abigail A. Hurst, Terence C. Jenkins, Lloyd R. Kelland, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 158 KB

english, 2000

21

Design and synthesis of novel pyrrolobenzodiazepine (PBD) prodrugs for ADEPT and GDEPT

Marina J Sagnou, Philip W Howard, Stephen J Gregson, Ebun Eno-Amooquaye, Philip J Burke, David E Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 176 KB

english, 2000

22

Synthesis of the first example of a c2-C3/C2′-C3′-endo unsaturated pyrrolo[2,1-c][1,4]benzodiazepine dimer

Stephen J Gregson, Philip W Howard, Kathryn E Corcoran, Terence C Jenkins, Lloyd R Kelland, David E Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 130 KB

english, 2001

23

Synthesis of the first examples of A-C8/C-C2 amide-Linked pyrrolo[2,1-c][1,4]benzodiazepine dimers

Stephen J. Gregson, Philip W. Howard, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

24

Chemical approaches to the discovery and development of cancer therapies

Neidle, Stephen, Thurston, David E.

Journal:

Nature Reviews Cancer

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

25

Defensive burying in the Mongolian gerbil (Meriones unguiculatus) as a function of size and shape of the test chamber

Stephen F. Davis, Scott A. Moore, Cynthia L. Cowen, Debra K. Thurston, John C. Maggio

Journal:

Learning & Behavior

Year:

1982

Language:

english

File:

PDF, 632 KB

english, 1982

26

Molecular Dynamics Studies of the STAT3 Homodimer:DNA Complex: Relationships between STAT3 Mutations and Protein–DNA Recognition

Husby, Jarmila, Todd, Alan K., Haider, Shozeb M., Zinzalla, Giovanna, Thurston, David E., Neidle, Stephen

Journal:

Journal of Chemical Information and Modeling

Year:

2012

Language:

english

File:

PDF, 941 KB

english, 2012

27

Clinical approach to formative evaluation. Tight production schedules and limited budgets? try a clinical approach

Albert J. Lowe, Walter I. Thurston, Stephen B. Brown

Journal:

Performance Improvement

Year:

1983

File:

PDF, 506 KB

1983

28

DNA interstrand cross-linking andin vivoantitumor activity of the extended pyrrolo[2,1-c][1,4]benzodiazepine dimer SG2057

John A. Hartley, Anzu Hamaguchi, Marie Suggitt, Stephen J. Gregson, David E. Thurston, Philip W. Howard

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 357 KB

english, 2012

29

Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries

Khondaker M. Rahman, Karolina Tizkova, Anthony P. Reszka, Stephen Neidle, David E. Thurston

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 372 KB

english, 2012

30

Design, Synthesis, and Evaluation of a Novel Sequence-Selective Epoxide-Containing DNA Cross-Linking Agent Based on the Pyrrolo[2,1- c ][1,4]benzodiazepine System

Wilson, Stuart C., Howard, Philip W., Forrow, Stephen M., Hartley, John A., Adams, Lesley J., Jenkins, Terence C., Kelland, Lloyd R., Thurston, David E.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 293 KB

english, 1999

31

Geometric Separators for Finite-Element Meshes

Miller, Gary L., Teng, Shang-Hua, Thurston, William, Vavasis, Stephen A.

Journal:

SIAM Journal on Scientific Computing

Year:

1998

Language:

english

File:

PDF, 804 KB

english, 1998

32

Long-term management of atopic dermatitis in infants with topical pimecrolimus, a nonsteroid anti-inflammatory drug

Kapp, Alexander, Papp, Kim, Bingham, Ann, Fölster-Holst, Regina, Ortonne, Jean-Paul, Potter, Paul C., Gulliver, Wayne, Paul, Carle, Molloy, Stephen, Barbier, Nathalie, Thurston, Mark, de Prost, Yves

Journal:

Journal of Allergy and Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 212 KB

english, 2002

33

Biaryl polyamides as a new class of DNA quadruplex-binding ligands

Rahman, Khondaker M., Reszka, Anthony P., Gunaratnam, Mekala, Haider, Shozeb M., Howard, Philip W., Fox, Keith R., Neidle, Stephen, Thurston, David E.

Journal:

Chemical Communications

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

34

Linker Length Modulates DNA Cross-Linking Reactivity and Cytotoxic Potency of C8/C8‘ Ether-Linked C2- exo -Unsaturated Pyrrolo[2,1- c ][1,4]benzodiazepine (PBD) Dimers

Gregson, Stephen J., Howard, Philip W., Gullick, Darren R., Hamaguchi, Anzu, Corcoran, Kathryn E., Brooks, Natalie A., Hartley, John A., Jenkins, Terence C., Patel, Sejal, Guille, Matthew J., Thurston

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 285 KB

english, 2004

35

Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system

Bose, D. Subhas, Thompson, Andrew S., Ching, Jingshan, Hartley, John A., Berardini, Mark D., Jenkins, Terence C., Neidle, Stephen, Hurley, Laurence H., Thurston, David E.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 784 KB

english, 1992

36

[American Institute of Aeronautics and Astronautics 36th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Las Vegas,NV,U.S.A. (24 July 2000 - 28 July 2000)] 36th AIAA/ASME/SAE/ASEE Joint Propulsion Conference and Exhibit - Flights of a laser-powered lightcraft during laser beam hand-off experiments

Mead, Jr., Franklin, Squires, Stephen, Beairsto, Chris, Thurston, Mike

Year:

2000

Language:

english

File:

PDF, 1.51 MB

english, 2000

37

Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity

Gregson, Stephen J., Howard, Philip W., Hartley, John A., Brooks, Natalie A., Adams, Lesley J., Jenkins, Terence C., Kelland, Lloyd R., Thurston, David E.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 269 KB

english, 2001

38

Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography

Nkansah, Edwin, Shah, Rahi, Collie, Gavin W., Parkinson, Gary N., Palmer, Jonathan, Rahman, Khondaker M., Bui, Tam T., Drake, Alex F., Husby, Jarmila, Neidle, Stephen, Zinzalla, Giovanna, Thurston, Da

Journal:

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

39

Prospective evaluation of nighttime hot flashes during pregnancy and postpartum

Thurston, Rebecca C., Luther, James F., Wisniewski, Stephen R., Eng, Heather, Wisner, Katherine L.

Journal:

Fertility and Sterility

Year:

2013

Language:

english

File:

PDF, 176 KB

english, 2013

40

Health and Environmental Consequences of the World Trade Center Disaster

Philip J. Landrigan, Paul J. Lioy, George Thurston, Gertrud Berkowitz, L. C. Chen, Steven N. Chillrud, Stephen H. Gavett, Panos G. Georgopoulos, Alison S. Geyh, Stephen Levin, Frederica Perera, Stephe

Journal:

Environmental Health Perspectives

Year:

2004

Language:

english

File:

PDF, 3.46 MB

english, 2004

41

Structure of a Covalent DNA Minor Groove Adduct with a Pyrrolobenzodiazepine Dimer: Evidence for Sequence-Specific Interstrand Crosslinking

Jenkins, Terence C., Hurley, Laurence H., Neidle, Stephen, Thurston, David E.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.40 MB

english, 1994

42

Effect of linker length on DNA-binding affinity, cross-linking efficiency and cytotoxicity of C8-linked pyrrolobenzodiazepine dimers

Bose, D. Subhas, Thompson, Andrew S., Smellie, Melissa, Berardini, Mark D., Hartley, John A., Jenkins, Terence C., Neidle, Stephen, Thurston, David E.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1992

Language:

english

File:

PDF, 373 KB

english, 1992

43

The prenylated dioxopiperazine alkaloid Cristatin A has selective telomeric DNA G-quadruplex stabilising properties

Rahman, Khondaker M., Hossain, Mohammad D., Sohrab, Mohammad H., Drake, Alex F., Bui, Tam T., Husby, Jarmila, Gunaratnam, Mekala, Neidle, Stephen, Hasan, Choudhury M., Thurston, David E.

Journal:

Chemical Communications

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012

44

Synthesis of a novel C2/C2′-exo unsaturated pyrrolobenzodiazepine cross-linking agent with remarkable DNA binding affinity and cytotoxicity

Gregson, Stephen J., Howard, Philip W., Thurston, David E., Jenkins, Terence C., Kelland, Lloyd R.

Journal:

Chemical Communications

Year:

1999

Language:

english

File:

PDF, 143 KB

english, 1999

45

Separators for sphere-packings and nearest neighbor graphs

Miller, Gary L., Teng, Shang-Hua, Thurston, William, Vavasis, Stephen A.

Journal:

Journal of the ACM

Year:

1997

Language:

english

File:

PDF, 637 KB

english, 1997

46

Gender-role identity after heart attack: Links with sex and subjective health status

Radley, Alan, Grove, Alyson, Wright, Stephen, Thurston, Herbert

Journal:

Psychology and Health

Year:

2000

Language:

english

File:

PDF, 777 KB

english, 2000

47

Ocular Motor Minisymposium: Chicago 1985, summary

Thurston, Stephen E.

Journal:

Neuro-Ophthalmology

Year:

1986

Language:

english

File:

PDF, 183 KB

english, 1986

48

Synthesis of Sequence-Selective C8-Linked Pyrrolo[2,1- c ][1,4]benzodiazepine DNA Interstrand Cross-Linking Agents

Thurston, David E., Bose, D. Subhas, Thompson, Andrew S., Howard, Philip W., Leoni, Alberto, Croker, Stephen J., Jenkins, Terrence C., Neidle, Stephen, Hartley, John A., Hurley, Laurence H.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 268 KB

english, 1996

49

Early Priming Minimizes the Age-Related Immune Compromise of CD8+ T Cell Diversity and Function

Valkenburg, Sophie A., Venturi, Vanessa, Dang, Thurston H. Y., Bird, Nicola L., Doherty, Peter C., Turner, Stephen J., Davenport, Miles P., Kedzierska, Katherine, Wherry, E. John

Journal:

Year:

2012

Language:

english

File:

PDF, 851 KB

english, 2012

50

The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex

Bentley, Stephen D., Comas, Iñaki, Bryant, Josephine M., Walker, Danielle, Smith, Noel H., Harris, Simon R., Thurston, Scott, Gagneux, Sebastien, Wood, Jonathan, Antonio, Martin, Quail, Michael A., Ge

Journal:

PLoS Neglected Tropical Diseases

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012